The SportsWire

Louisville at Syracuse

Prediction · week 7, 2026 · Sat Oct 17, 6:30 PM CT / 7:30 PM ET · JMA Wireless Dome (Syracuse)

Updated Tue Oct 13, 7:56 PM CT

The prediction

Our call: Louisville by 11.0Strong

All three models favor Louisville. The line, shown for comparison only, has Louisville by 12.5.

The average of SP+, Elo and Our model; the line is left out and kept as a benchmark. Toss-up under 3 points, Lean 3 to 7, Strong 7 and over. More ›

SP+ has Louisville by 10.9, Elo has Louisville by 14.5, and Our model has Louisville by 7.6. They are within 6.9 points of each other.

Every model

ModelSays
SP+
Louisville +13.0 vs Syracuse -0.4
Louisville by 10.9
Elo
Louisville 1729 vs Syracuse 1303
Louisville by 14.5
Our model · experimental
Louisville +9.8 vs Syracuse -0.3
Louisville by 7.6
Line (benchmark)
pregame line
Louisville by 12.5
Our call
average of SP+, Elo and Our model · Strong
Louisville by 11.0

Each margin is from the same weekly ratings the team pages use: SP+ and Elo from their rating gap, the home team given 2.5 points (none at a neutral site); Our model is this site's experimental rating; the line is the market's pregame margin, shown as a benchmark and never part of Our call. How these work ›

Key injuries

Louisville

No injury report yet for this game. First reports usually come Wednesday.

Syracuse

No injury report yet for this game. First reports usually come Wednesday.

Last 5 meetings

Louisville leads 13–8 · last: Syracuse 31–7, 2022

SeasonResultSite
2022Syracuse 31–7JMA Wireless Dome
2021Louisville 41–3L&N Federal Credit Union Stadium
2020Louisville 30–0L&N Federal Credit Union Stadium
2019Louisville 56–34L&N Federal Credit Union Stadium
2018Syracuse 54–23JMA Wireless Dome

Team pages